A Crack in Creation: The New Power to Control Evolution

World-famous scientist Jennifer Doudna - winner of the 2020 Nobel Prize in Chemistry for creating the revolutionary gene-editing technique CRISPR - explains her discovery, describes its power to reshape the future of all life and warns of its use.

'AN INSTANT CLASSIC' Siddhartha Mukherjee

A handful of discoveries have changed the course of human history. This book is about the most recent and potentially the most powerful and dangerous of them all.

It is an invention that allows us to rewrite the genetic code that shapes and controls all living beings. As a result, dreams of genetic manipulation have become a stark reality: the power to cure disease and alleviate suffering, as well as to re-design any species, including humans, for our own ends.

Jennifer Doudna is the co-inventor of this technology - known as CRISPR - and a scientist of worldwide renown. Writing with fellow researcher Samuel Sternberg, here she provides the definitive account of her discovery, explaining how this wondrous invention works and what it is capable of. She also asks us to consider what our new-found power means: how do we enjoy its unprecedented benefits while avoiding its equally unprecedented dangers?

'The future is in our hands as never before, and this book explains the stakes like no other' George Lucas

'One of the most PIONEERING women in science . . . Exhilarating' Arianna Huffington

'Thrilling' Adam Rutherford

Too important … What may happen thanks to Doudna’s [discovery] is dizzying … for her, this is the future of medicine. If she’s right, then Crispr is about to make our present healthcare concerns look surprisingly trivial -- Bryan Appleyard, Sunday Times

One of the architects of this miraculous biological technique … explains the science clearly and excitingly as a kind of globalist detective story, Telegraph

Probably the greatest biological breakthrough since that of Francis Crick, James Watson and Rosalind Franklin… We owe Doudna several times over – for her discovery, for her zeal to take it from the lab into the clinic, for her involvement in the ethical issues raised, for her public engagement work, and now for this book -- Peter Forbes, Guardian

An urgent plea from the celebrated biologist whose discovery enabled us to rewrite the code of life. The future is in our hands as never before, and this book explains the stakes like no other -- George Lucas